Group 1B: HER2+ Breast Cancer; Brain Metastasis



Wednesday, Dec 14
10:00 am – 11:30 am Eastern Time (US/New York)



Poster #P4-01-36

Real world data for Trastuzumab Deruxtecan in HER2-positive metastatic breast cancer patients with brain metastases

Poster #P5-14-10:

Targetable alterations and genomic signatures within breast cancer brain metastases: Data from comprehensive genomic profiling of 761 breast cancer brain metastases

Mentor: Ellen Landsberger, M.D.

Ellen is a retired OBGYN/Maternal Fetal Medicine specialist and since then has pursued her other passion- politics, especially related to women’s health. She has been living with breast cancer for 27 years but did not get involved in advocacy until she was diagnosed with, and treated for metastatic breast cancer (MBC) in 2017. She is a patient advocate at Memorial Sloan Kettering Cancer, the Translational Breast Cancer Research Consortium, and the IMAXT project out of CRUK – Cancer Research of United Kingdom. Ellen is a Project LEAD graduate and enjoys lobbying with the National Breast Cancer Coalition. She recently joined the MBC Alliance as an independent patient advocate and is excited to join GRASP as a patient advocate mentor. Ellen lives in NYC and goes to as many concerts and theater productions as she can!

Twitter: @EllenLands

Scientist: Isaac Chan, M.D., Ph.D.

Dr. Isaac Chan is a physician-scientist who is dedicated to eliminating mortality associated with metastatic breast cancer. During his MD/PhD training at University of North Carolina and medical oncology fellowship at Johns Hopkins University, he developed the tools to execute a bench to bedside research vision that probes the relationship between breast cancer metastasis and the tumor environment. His research focuses 1) understanding how metastatic tumor cells can grow in distant organs and 2) discovering novel drug targets that activate a patient’s own immune cells to target metastatic cancer lesions. He chose UT Southwestern to launch his lab because of its strong laboratory-based history and foundation and the innumerable opportunities to apply basic science knowledge to clinical practice. In parallel to his research efforts, he continues to see patients, who inform and inspire his work in the lab. Outside of medicine, his interests include spending time with family and friends, cooking, and reading biographies and books on American history.

Twitter: @ithinkichan