Scientist: Isaac Chan, M.D., Ph.D.
Dr. Isaac Chan is a physician-scientist who is dedicated to eliminating mortality associated with metastatic breast cancer. During his MD/PhD training at University of North Carolina and medical oncology fellowship at Johns Hopkins University, he developed the tools to execute a bench to bedside research vision that probes the relationship between breast cancer metastasis and the tumor environment. His research focuses 1) understanding how metastatic tumor cells can grow in distant organs and 2) discovering novel drug targets that activate a patient’s own immune cells to target metastatic cancer lesions. He chose UT Southwestern to launch his lab because of its strong laboratory-based history and foundation and the innumerable opportunities to apply basic science knowledge to clinical practice. In parallel to his research efforts, he continues to see patients, who inform and inspire his work in the lab. Outside of medicine, his interests include spending time with family and friends, cooking, and reading biographies and books on American history.