Group 2E: Immune Microenvironment, Novel Targets, Male Breast Cancer

Thursday, Sept 15
2:00 pm – 3:30 pm Eastern Time (US/New York)

Poster #1: 

Augment T-Cell Activity to Treat Breast Cancer Metastases

Poster #2:

The Influence of Sex on the Immune Microenvironment in Male and Female Breast Cancer

Poster author Ebony Hargrove-Wiley, Ph.D. Candidate will attend this session

Mentor: Kelly Shanahan, M.D.

In 2008, Kelly Shanahan had everything going for her: a busy and successful ob-gyn practice; a precocious 9-year- old daughter; and a well used passport from traveling all over the world with her family to attend conferences, with a liberal dose of vacation on the side. When she was diagnosed with stage IIB breast cancer in April, she considered it a mere bump in the road.

And for five years, breast cancer was an aside, something to put in the past medical history section of forms. Even when she developed sudden back pain, Kelly never thought it could be breast cancer rearing its ugly head – a pulled muscle, a herniated disc maybe, but not what it turned out to be: metastatic breast cancer in virtually every bone in her body, with a fractured vertebrae and an about to break left femur. Kelly was diagnosed on her 53rd birthday.

Neuropathy from the chemo did cost her her career, but she has found a new purpose in advocacy. Kelly is on the board of METAvivor, a member of the Metastatic Breast Cancer Alliance, a Komen Advocate in Science, a grant reviewer and research advocate. Kelly Shanahan is a mother, a wife, a daughter, a doctor, a woman LIVING with metastatic breast cancer.

Twitter: @stage4Kelly

Scientist: Meenakshi Anurag, Ph.D.

Meenakshi believes that cancer is a diverse and heterogeneous disease; hence one therapy will not be uniformly beneficial to all patients. To dissect heterogeneity at the molecular level, her research lab employs multi-omics analysis on data generated from patient tumors.  She implements integrated bioinformatic approaches to understand the role of mutations, structural variations, gene expressions, genomic alterations, proteomic and phospho-proteomic signatures in promoting cancer or driving drug resistance.  Her research lab focuses on improving cancer diagnosis, treatment, and survival by employing data science in precision medicine.