Group 3A: Novel Targets, Treatment Resistance, Triple Negative Breast Cancer

Thursday, Sept 15
6:00 pm – 7:30 pm Eastern Time (US/New York)

Poster #1: 

Epithelial to Mesenchymal Transition Confers Sensitivity to Cytotoxic Agent Ophiobolin A via Alterations in Mitochondrial Function and Metabolic Pathways

Poster author Haleigh Parker will attend this session

Poster #2:

Mitochondrial Structure and Function Adaptation in Residual Triple Negative Breast Cancer Cells Surviving Chemotherapy Treatment

Poster author Lily Baek, Ph.D. will attend this session

Mentor: Bob Riter, MHSA

Bob Riter has been active in cancer advocacy and education since his diagnosis with breast cancer in 1996. More recently, he was diagnosed with prostate cancer and was found to have a CHEK2 mutation. For many years, he was the executive director of the Cancer Resource Center of the Finger Lakes, a locally-focused support organization in Ithaca, NY. Now, Bob is the patient advocate with Cornell University’s Physical Sciences Oncology Center where he works to connect cancer researchers, students, and the local cancer community. He’s written many newspaper columns about his experiences in the cancer world and likes to build bridges between patients, researchers, family members, and clinicians.

Twitter: @bobriter

Scientist: Jamie Spangler, Ph.D.

Dr. Jamie Spangler’s research aims to expand the repertoire of protein therapeutics by redesigning naturally occurring proteins and engineering new molecules to overcome the deficiencies of existing drugs. Integrating cutting-edge tools from structural biophysics, biomolecular engineering, and translational immunology, her research focuses on developing innovative platforms for the discovery and design of proteins that recruit novel mechanisms for disease therapy. In particular, Spangler’s group is interested in engineering antibody-based molecules that reshape immune cell behavior for targeted treatment of cancer, infectious diseases, and autoimmune disorders. The overarching goal of her interdisciplinary research program is to establish new insights into protein behavior and the extent to which it can be manipulated for medically relevant applications.

Twitter: @SpanglerLab