Group 3D: Leptomeningeal Disease; Brain Metastasis; Predictive Biomarkers

Wednesday, Dec 14 6:00 pm – 7:30 pm Eastern Time (US/New York)

Poster #P1-05-23

Optimizing the diagnosis of leptomeningeal metastases in breast cancer patients by circulating tumor cells and circulating tumor DNA

Poster #P2-21-05:

Vascular effects of Platelet-derived growth factor-B (PDGFB) in breast cancer metastasis to the brain

Poster authors Sajita Shah, Ph.D. & Gina Sizemore, Ph.D. will attend this session

Mentor: Julia Levine

Julia is a metastatic lobular breast cancer thriver of almost 9  years. She is a metastatic patient advocate and a founding member of the Lobular Breast Cancer Alliance (LBCA). She is currently the Lead Research Advocate and Publications/Clinical trials Curator for LBCA, a member of  Metastatic Breast Cancer Alliance, the liaison between LBCA and the Metastatic Breast Cancer Project, Living Beyond Breast Cancer, and She has been a GRASP mentor and advocate participant since 2019.  She is also an advocate co-author on “Decreased enrollment in breast cancer trials by histologic subtype: does invasive lobular carcinoma resist RECIST? , published in NPJ Breast Cancer in Oct. 2021. 

Julia participates in research advocacy to advance her knowledge, educate others, and provide a patient perspective in the development and implementation of studies in both metastatic and lobular breast cancer. Her background as a metastatic patient combined with her advocacy experience gives her a unique perspective with which to educate and help facilitate important advances in breast cancer research and specifically lobular research.

Twitter: @jackel626

Scientist: Bisrat Debeb, Ph.D.

Bisrat Debeb completed his Ph.D. at Texas A&M University in 2008 and is currently an Assistant Professor in the Section of Translational Breast Cancer Research in the Department of Breast Medical Oncology, Division of Cancer Medicine at MD Anderson Cancer Center. The Debeb Laboratory focuses on understanding the molecular and cellular mechanisms of breast cancer dissemination to the brain, and on investigating the molecular and biological processes underlying the aggressive pathobiology of inflammatory breast cancer (IBC), an aggressive variant of breast cancer. His lab has established preclinical mouse models of brain metastasis to uncover novel mechanisms and test the efficacy of new therapeutic agents. His team conducts both basic laboratory investigation and translational breast cancer research with an overarching goal of developing novel therapeutic strategies to improve survival of patients with aggressive breast cancer.