Group 5A: Triple Positive; HR+ Breast Cancer; Novel Treatments; Predictive Biomarkers; Hormone Therapy & Resistance

Thursday, Dec 15
2:00 pm – 3:30 pm Eastern Time (US/New York)

Poster #PD10-01

Impact of ESR1 mutations on selective estrogen receptor degraders and modulators: An integrated liquid-biopsy and pharmacodynamics approach

Poster author Lorenzo Gerratana, M.D. will attend this session

Poster #P3-07-16:

Pre-clinical study of amcenestrant and HER2-targeted therapies in HER2+/ER+ breast cancer cell line models

Poster author Amira Mahdi, Ph.D. will attend this session

Mentor: Katie Edick

Katie Edick has been living with metastatic breast cancer (MBC) since 2016.  She has been a pediatric occupational therapist for 21 years.

Katie has volunteered with Little Pink Houses of Hope leading yearly retreats for families going through breast cancer. She provides mentoring to other MBC patients through Imerman Angels. Katie is engaging more with patient advocacy through sharing her story on local news programs, senate hearing committees, and podcasts to help educate and advocate for legislation and research to support families going through a breast cancer diagnosis. Currently, she is the social media coordinator for the Michigan Breast Cancer Coalition. She sits on two different workgroup committees in Michigan’s Department of Health & Human Services for young women with breast cancer; the advisory committee and the metastatic breast cancer committee. She attended the NBCC Advocate Leadership Summit and engaged with local legislators during that campaign, and has attended the annual Metastatic Breast Cancer Research Conference for three years. Check out her blog at

Twitter: @KatieEdick

Scientist: Shaheen Sikandar, Ph.D.

Shaheen got her Ph.D. at the University of California – Irvine followed by a post-doctoral fellowship at Stanford University. Shaheen is currently an Assistant Professor of Molecular, Cellular, and Developmental Biology at University of California – Sant Cruz. The Sikandar lab has identified critical regulators of breast cancer metastasis and her team aims to understand the molecular mechanisms that govern metastasis formation including signals from the microenvironment. Her research focuses on studying molecular changes in mammary stem cells during aging and how these changes affect breast cancer risk cancer which will lead to the development of better preventive and therapeutic strategies for breast cancer. When not doing/thinking about science, Shaheen spends her time with her two energetic boys hiking, kayaking, and exploring new places to eat in the bay area.

Twitter: @ssikandar